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Special Populations Renal Insufficiency A single-dose, open-label study was conducted to evaluate the pharmacokinetics of Januvia (50 mg dose) in patients with varying degrees of chronic renal insufficiency compared to normal healthy control subjects

5,10 Moreover, the multifaceted functions of GLP-1 RAs extend into the realm of brain activity, particularly exhibiting neuroprotective effects

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[DOI] [PubMed] [Google Scholar] 226.Wang H., Yang T., Shen Y., Wan C., Li X., Li D., Liu Y., Wang T., Xu D., Wen F., et al

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Tirzepatide is a roughly 4,813-dalton peptide, and digestive enzymes break peptides down before systemic absorption