tirzepatide mood swings & Anxiety: Mental Health Effects Explained Does tirzepatide cause increased depression?

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Glucose-dependent insulinotropic polypeptide receptor agonism for treating metabolic conditions was initially dismissed due to concerns that GIP receptor agonists (GIP RA) fail to stimulate insulin secretion in patients with type 2 diabetes, stimulate glucagon secretion worsening hyperglycaemia, and contribute to obesity [57]

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This should be discussed with the provider

doi: 10.1016/S0140-6736(17)31585-4 83