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Acetyl-L-carnitine confers neuroprotection against lipopolysaccharide (LPS) -induced neuroinflammation by targeting TLR4/NFB, autophagy, inflammation and oxidative stress

Paraxanthine has been shown to increase BDNF levels to a greater extend compared to caffeine in a preclinical study [10], which translated in increased cognitive performance in a clinical study investigating the ability to shift between tasks [34]

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These findings suggest that tirzepatide confers cardiovascular benefits at least comparable to established GLP-1RAs