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However, liver function should be monitored during treatment, particularly during dose escalation when the metabolic demands on the liver increase

Consider pausing and consulting a doctor if: Your symptoms have not improved at all after two full weeks

Orlistat is indicated for patients with a BMI 30 kg/m 2 or 28 kg/m 2 in association with other risk factors (e.g., hypertension, diabetes, hyperlipidaemia) [10]

The reconstitution ratios don't match

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It can up-regulate CPT1A by directly acting on peroxisome proliferator response elements (PPREs) in CPT1A introns, as well as via activating PPAR (Le May et al., 2005)