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Fertil Steril 1978;29:5863.Google Scholar Lyon, RP, Marshall, S, Scott, MP

When transported into the mitochondria, the glycolytic end-product pyruvate is decarboxylated to produce acetyl-CoA by PDH complex, which reduces NAD + to NADH simultaneously

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In times of high toxic load or when someone is focused on supporting liver markers, a 1500 mg dose may be utilized to provide the liver with the raw materials it needs to keep up with demand