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doi: 10.1517/14656566.2012.642866 60 FDA Drug Safety Communication

GF mice exhibit altered gutbrain metabolic signaling, with changes in EEC number, as well as differences in intestinal nutrient-sensing machinery and nutrient-induced gut peptide release compared to conventional mice 242

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This suggests that the reformation of the SQ . from H 2 Q is mechanistically important during the redox metabolism of doxorubicin