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Peptides are chains of amino acids, and in solution they are chemically fragile

It explains why folate supplementation (particularly with 5-MTHF rather than folic acid in T/T individuals) improves endothelial function and reduces arterial stiffness in published clinical trials effects that operate partly through homocysteine lowering and partly through BH4 recycling restoration and improved eNOS coupling efficiency

However, this comparison should not be interpreted as suggesting that AOD-9604 produces identical benefits to full GH, as the mechanisms and effects differ substantially

ISBN 978-1-4987-5429-3

(PubMed) Graham DY, Anderson SY, Lang T

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