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Under cystine-starved conditions, GSH supplementation rescued the phosphorylation of p70S6K (T389) and S6 (S235/236) of the mTORC1 pathway and relieved the induction of phospho-GCN2 (T899), phospho-eIF2 (S51) and ATF4 of the ISR system (Fig

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Ferrara F, Verduci C, Laconi E, Mangione A, Dondi C, Del Vecchio M, Carlevatti V, Zovi A, Capuozzo M, Langella R (2024) Therapeutic advances in psoriasis: from biologics to emerging oral small molecules