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Transdermal delivery bypasses the GI tract, which could alter both the effective dose range and the side effect profile

These shifts happen because GLP-1 signaling dampens the release of hunger hormones like ghrelin while boosting satiety signals from cholecystokinin and peptide YY

Our data also reveal an antiapoptotic role for GLP-1(2836) through activation of sAC and its downstream cAMP-PKA effectors

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