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GLP-1 receptor agonists should be avoided in patients with a history of medullary thyroid cancer or MEN2

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On the pharmacology side, HGF-induced MET activation exerts beneficial neuroprotective effects also in adulthood, specifically in neurodegenerative disease, and in preclinical models of cerebral ischemia, spinal cord injuries, and neurological pathologies, such as Alzheimers disease (AD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS)

Empirical Bayes moderationwith trend and robust optionswas applied to stabilize variance estimates

Epidural steroid injections provide faster symptom relief but do not promote tissue repair

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