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A 2-year, more-closely monitored trial in 74 patients with diabetes reported a similar level of adverse events as the UKPDS, and no serious adverse events were considered to be related to acarbose [93]

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Eli Lilly and Company Lilly's triple agonist, retatrutide, demonstrated significant reductions in A1C and weight in first Phase 3 trial for treatment of type 2 diabetes

The new peptide, however, turned out to slow down the stomach's processing of food and cause weight loss (Winkler, Cohen)

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