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Remember that most side effects improve with time

Effects of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on all-cause mortality and renal outcomes in patients with diabetes and albuminuria: a systematic review and meta-analysis

It is crucial to note that the prescribing information for both drugs did not disclose any risks associated with similar gastrointestinal events or issue warnings regarding the potential development of gastroparesis

The most pronounced differences were observed in gastrointestinal and metabolic events: nausea (combination: n = 9651 vs monotherapy: n = 38,030), vomiting (4383 vs 17,062), pancreatitis (1389 vs 6655), and hypoglycemia (773 vs 1778)

Receptors 4, 2 (2025).

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