In hidradenitis suppurativa (HS), there appears to be a dysregulated adipokine release that is shifted towards pro-inflammatory adipokines
(PubMed) Beld J, Sonnenschein EC, Vickery CR, Noel JP, Burkart MD
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Interestingly, homocysteine levels have been positively associated with serum GGT, suggesting elevations in homocysteine may at least partly be due to increased shunting toward glutathione synthesis in response to increased GSH demands, though this has not been proven as of yet
(By the way, you can read more about NAC and other options for glutathione supplementation, along with safety guidelines and best practices in What to Avoid When Taking Glutathione)
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