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Multiomics confirm mitochondrial adaptations in response to SHP2/MEK inhibition To investigate the underlying properties of the screening response of our cell lines, we performed metabolomic, proteomic, and transcriptomic analyses

Centrally, GLP-1, primarily produced by neurons in the nucleus of the solitary tract (NTS), modulates appetite and body weight through widespread neural projections (19,20)

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Circulating levels of intestinal fatty-acid binding protein, which should be undetectable in the plasma under healthy conditions, were significantly elevated with alcohol exposure

DOI: 10.1007/s00018-005-4560-2