The UKPDS study randomized patients to either first (chlorpropamide) or second (glibenclamide) generation sulfonylureas, but did not report differences in outcomes between the two
2010;2(3):a000158
However, it is not FDA-approved for human use and cannot legally be marketed as a drug, supplement, or for human consumption
Recommended dosage is 0.25mg for the first 4 weeks, then 0.5mg for the next 4 weeks
High doses of acetaminophen can deplete glutathione stores in the liver, potentially leading to hepatotoxicity
Tenille Davis, chief advocacy officer for the Alliance for Pharmacy Compounding, told legislators that parts of AB 1990 restate conduct that is already prohibited and might make it harder for pharmacists to explain the clinical rationale for compounded options, according to CALMATTERS