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Future studies should validate these targets in preclinical models and explore their translational potential to develop interventions improving the outcomes of patients with SAE

(2012) 129:e2516

Some researchers report usable potency beyond 28 days when stored properly, though 28 days remains the standard safety recommendation

However, its metabolism can generate ROS, which include both radical (e.g., superoxide O 2 , hydroxyl radical OH) and non-radical species (e.g., hydrogen peroxide H 2 O 2 ) [160]

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