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The trial evidence is strongest for concentrations in the 0.1% to 1% range

It's best to avoid drinking alcohol with milk thistle, as alcohol can worsen liver damage and counteract any potential supportive effects of milk thistle

Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA

While supplements may be appropriate for some people, they may not be safe for everyone, and they could interact with other medications a person is taking

Mol Endocrinol (2013) 27(11):196979.10.1210/me.2013-1178 145 BennettAMTangTLSugimotoSWalshCTNeelBG

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