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Close Monitoring: Pay close attention to any changes in your mood, anxiety levels, sleep patterns, and overall mental well-being after starting or adjusting the dosage of a GLP-1 inhibitor

[1] Other safety considerations include risk of gallbladder disease, pancreatitis, diabetic retinopathy complications (particularly with rapid A1c reduction), and hypersensitivity reactions

They were assigned 10 or 15 mg of tirzepatide or placebo for 52 weeks

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Figure 2

Oral Glutamine Supplementation Reduces Obesity, Pro-Inflammatory Markers, and Improves Insulin Sensitivity in DIO Wistar Rats and Reduces Waist Circumference in Overweight and Obese Humans