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Neuroprotection of agomelatine against cerebral ischemia/reperfusion injury through an antiapoptotic pathway in rat

We observe that all the GluK3 N-glycan mutants recovered from glutamate-evoked desensitized state faster than the wild type receptors with a rec of 0.5 s (Asn 247) (unpaired t-test, P = 0.0870)

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In controlled clinical studies as both monotherapy and combination therapy with metformin or pioglitazone, the overall incidence of adverse reactions, hypoglycemia, and discontinuation of therapy due to clinical adverse reactions with Januvia were similar to placebo

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