When transported into the cells, Gln can be catabolized by several enzymes, including glutaminase (GLS), carbamoyl-phosphate synthase (CPS/CAD), and glutamine phosphoribosyl pyrophosphate (PRPP) amidotransferase (GPAT)
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This creates more controllable conditions for subsequent OI or ART, rather than serving as a direct means to induce ovulation or guarantee pregnancy. 8.2 Stratified clinical strategies by phenotype and reproductive intent As evidence for metabolic benefits currently outweighs that for hard ART endpoints, treatment decisions should be stratified by metabolic risk and the reproductive timeline