doi: 10.1016/j.jmmm.2004.02.030 14 FerraroM
A 2014 paper summarized the role of cortisone in tendinopathies this way, Overall it is clear that the local administration of glucocorticoid has significant negative effects on tendon cells in vitro, including reduced cell viability, cell proliferation and collagen synthesis.There is increased collagen disorganisation and necrosis as shown by in vivo studies.The mechanical properties of tendon are also significantly reduced.This review supports the emerging clinical evidence that shows significant long-term harms to tendon tissue and cells associated with glucocorticoid injections. Another 2014 paper gives one possible mechanism for cortisones damaging effect on tendons
Summary: Building a Smart Research Stack A good research stack is engineered, not improvised
The Mental Health Benefits of NAD+ NAD+ (Nicotinamide adenine dinucleotide) therapy has shown promise in improving mental health outcomes in a variety of settings
The recent shift in perspective from viewing oxidants as merely damaging agents to key signaling molecules is an important one, and one which places GSH homeostasis as a central mediator of these communications
Third, pharmacological agents possessing antioxidant properties, such as GSH ester, N -acetylcysteine, and vitamins, and antioxidant inducers diminish alcohol-induced liver damage in experimental models
