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For researchers investigating chronic low-grade inflammation (often called inflammaging), it offers a well-characterized tool compound for studying simultaneous antioxidant and anti-inflammatory responses without the systemic suppression that comes from corticosteroids or broad NSAIDs

This increased glutathione pool may help contend with the increased flow of free radicals from dysfunctional mitochondria

However, while these findings are promising, the lack of large-scale clinical trials specifically investigating quercetin in AP remains a gap in the literature, and its therapeutic potential must be tested in rigorous clinical settings.Additionally, quercetins immunomodulatory effects, particularly its ability to promote M2 macrophage polarization, enhance the resolution of inflammation and facilitate tissue repairkey processes in the recovery from AP

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Therefore, ensuring adequate levels of other key antioxidants can also support glutathione levels

This will be an important direction for future research