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2A, compared with VRK2-KO cells downregulating the paralog genes involved in the GSH metabolic pathway, VRK2-KO cells with GCLC, GSS, and especially SLC7A11 knockdown exhibited increased ROS level, decreased GSH level and cellular viability

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More testing is needed

A review on the pharmacological effects of vitexin and isovitexin

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10.1124/jpet.112.199497 33 MiyazawaT.MatsumotoK.OhmichiH.KatohH.YamashimaT.NakamuraT