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Pierzchliska et al., 2021), so much so in fact that it has been argued that Alzheimers may be just as much a vascular disease as a neurological one (DAndrea, 2016

Cell (2012) 149(4):87185

Specifically, as an endogenous ligand of the aromatic hydrocarbon receptor, trans-3-indoleacrylic acid upregulates the expression of aldehyde dehydrogenase 1 family member A3, leading to increased production of NADH by utilizing retinol as a substrate

Interestingly, three of the compounds tested in our study present a promising antiparasitic activity

doi: 10.1073/pnas.2332354100 59 OMalleyYQAbdallaMYMcCormickMLReszkaKJDenningGMBritiganBEet al