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NAPQI rapidly forms adducts with critical cellular proteins, impairs mitochondrial membrane integrity, and results in a profound production of reactive oxygen species (ROS) within hepatocytes 5

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RNA sequencing (RNA-seq) and further verification showed that glycine modulates ferroptosis by inhibiting the expression of FTH1 and GPX4 and promoting the expression of S-adenosylmethionine in RA-FLS (132)