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The Q227E mutant, on the other hand, exhibited almost 10-fold reduction in K m for prephenate (2.7 mM), while the catalytic efficiency ( k cat / K m ) was reduced by 60-fold (0.1 vs

However, some patients have concerns about the potential risks these medications pose for thyroid cancer

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Anxiety or psychological factors Starting a new medication, especially one that affects your appetite and how your body feels, can be stressful