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The pharmaceutical composition comprises semaglutide and pharmaceutically acceptable excipients selected from the group consisting of permeation enhancer, binders, solubilzer, diluents, disintegrants, lubricants, glidants, antioxidants, pH adjusting agents, flavouring agent, colorants and sweetening agent etc

doi: 10.1016/j.jds.2012.11.005 56 PatrickRJFenskeNAMessinaJL

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39 The previous study suggested that mouse CBS is regulated by NRF2, likely through an ARE in the upstream region of the gene