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doi: 10.1038/mp.2016.196 169 YangWSSriRamaratnamRWelschMEShimadaKSkoutaRViswanathanVSet al

By installing a small, well-defined ring, we can tune how long the drug lasts, how stable it is, and even how it signalsall while staying compatible with the complex structures already in use. Reference: Leader-Independent C-Terminal Modification by a Radical S-Adenosyl-l-methionine Maturase Enables Macrocyclic GLP-1-Like Peptides by Jacob K

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They are an excellent preventive measure to keep you healthy during times of increased stress or exposure to pathogens

A clinical trial funded by the manufacturer of the medication supports this claim