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Loss of astrocytic glutamate transporters in Wernicke encephalopathy
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This increases cost without clear benefit and eliminates the ability to increase dose if initial response is insufficient
It modulates neutrophil and macrophage activity to dampen tissue-damaging inflammation and promotes clearance of infection
Chin Med J 126:45174523 Wong BW, Marsch E, Treps L, Baes M, Carmeliet P (2017) Endothelial cell metabolism in health and disease: impact of hypoxia
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