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Kim and Seok 2020)

Importantly, hormone sampling in patients treated with semaglutide was conducted without a washout period

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Clinical Evidence on GLP-1 and Oral Contraceptive Interactions Large randomized trials of semaglutide (STEP trials) and tirzepatide (SURMOUNT trials) did not formally measure contraceptive failure rates, because most participants were not actively using hormonal birth control

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Fortunately, advancements in medical research have led to the development of oral GLP-1 medications, offering an alternative for those who may be needle-averse