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Once stores are depleted, deficiency symptoms can progress rapidly, affecting haematological and neurological systems

Symptoms of vitamin B12 deficiency: extreme tiredness a lack of energy pins and needles a sore and red tongue mouth ulcers muscle weakness problems with your vision psychological problems, which can range from mild depression or anxiety to confusion and dementia problems with memory, understanding and judgement Causes of a vitamin B12 deficiency: pernicious anaemia a lack of these vitamins in your diet medicine certain medicines, including anticonvulsants and proton pump inhibitors (PPIs), can affect how much of these vitamins your body absorbs

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With 2 mL of water and a 1 mg daily dose (4 units), the vial lasts 50 days

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Unperturbed cytotoxic lymphocyte phenotype and function in myalgic Encephalomyelitis/Chronic fatigue syndrome patients