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159 If symptoms continue despite these measures, dose de-escalation is considered because the incidence and severity of adverse effects are dose-dependent, with higher doses associated with a higher incidence and severity of complaints
Related: Chatbots in Healthcare: Use-Cases and Best Practices For GLP-1 patients specifically, structured check-ins around common side effects nausea, appetite changes, injection site reactions give providers early warning signals and reduce unnecessary telehealth visits
This is why virtually all clinical research on Melanotan II has used subcutaneous injection
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