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This rebound occurs because semaglutide masks underlying hunger signals and metabolic patterns rather than permanently rewiring them, meaning your body's natural appetite-regulation pathways remain unchanged once the drug leaves your system
Treatment with liraglutide effectively alleviated central sensitization associated with CM [94] (Fig
PiessevauxHDe WinterBLouisEMulsVDe LoozeDPelckmansPet al
However, there is a second type of maintenance: staying at your new weight once the goal is reached
Providers typically start with a low dose and gradually increase it to minimize side effects
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