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showed the impact of gut microbiota on the fate of CD8 + T-cells through the production of SCFAs in mice consuming a high-fiber diet (Figure 1) (171)

10.4103/0019-5154.48978 Indian J Dermatol

Pregnancy and lactation safety has not been systematically studied, and as with most cosmetic and research compounds lacking definitive pregnancy safety data, conservative practice typically suggests avoiding use during pregnancy unless clearly needed, though the natural occurrence of GHK-Cu in the body and minimal systemic absorption from topical use suggest risk is likely to be low

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Future work should also explore the significant practical applications and the broader socio-economic and policy implications of fully adopting a hormesis-based framework in the food sector