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Supplementary information Rights and permissions Springer Nature or its licensor (e.g
Yes, especially during the first 4 to 8 weeks when calorie intake drops significantly and the body has not yet adapted to lower energy availability
Xie C, Alkhouri N, Elfeki MA
JCI Insight 8:e170671 Delvadia P, Dhote V, Mandloi AS et al (2025) Dual GLP-1 and GIP agonist Tirzepatide exerted neuroprotective action in a parkinsons disease rat model
Many patients do beautifully at doses that would be considered subtherapeutic by weight loss clinic standards
Approval status, labeling, contraindications, and any boxed warnings are all still undetermined
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