If your plan does not cover GLP-1 medications, compounded alternatives through telehealth start at $99 to $199 per month
So I'm not 100% picking sides
Compared to the control group, GLP-1RAs were associated with significant reductions in weight (mean difference (MD) = -5.70 kg, 95% confidence interval (CI): -9.52 to -1.88), BMI (MD = -2.94 kg/m 2 , 95% CI: -5.60 to -0.28), WC (MD = -3.66 cm, 95% CI: -4.89 to -2.43), glycated hemoglobin A1c (HbA1c) (standardized mean difference (SMD) = -0.73, 95% CI: -1.14 to -0.32), and systolic blood pressure (SBP) (MD = -3.62 mm Hg, 95% CI: -5.51 to -1.73) after cessation of therapy
OFA also submitted a comment to the FDA that argues the semaglutide shortage remains ongoing: OFA conservatively estimates that roughly 80 million prescriptions for semaglutide were fulfilled with compounded semaglutide in the last 12 months, inclusive of 503A pharmacy compounders and 503B outsourcing facilities
Gigliotti et al., 2025): Adapt to changing hunger cues and find a sustainable eating rhythm Manage GI symptoms through pacing, hydration, and fiber adjustments Understand the importance of resistance exercise and protein intake to preserve muscle mass and prevent excessive metabolic slowdown Stay nourished while balancing medication side effects and real-life routines Regular follow-up is key
Your compounding pharmacy has facility-specific guidance for your prescription
