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It plays a crucial role in regulating blood sugar levels, appetite, and digestion

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A small-molecule antagonist of HIF2alpha Is efficacious in preclinical models of renal cell carcinoma

These obese mice also showed activation of microglia and astrocytes and significant immunoreactivity of neuroinflammatory and apoptosis markers, such as TNF-, COX-2, and Caspase-3, in addition to lower expression of neurogenesis and synaptic plasticity markers, such as NeuN, KI-67, CREB-p, and BDNF

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