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The goal is finding the minimum effective dose for your specific response, not automatically pursuing the maximum studied amount

One intriguing hypothesis is that AgRP neurons, which are activated by prolonged fasting and necessary for adequate feeding response to negative energy balance in rodents, and which are inhibited by GLP-1RAs (68, 76, 93, 158, 159), could represent a key neural target for weight loss maintenance (160)

Michelle Seguin, MD Medical Reviewer Michelle Seguin, MD, is a board-certified family medicine, lifestyle medicine, and certified functional medicine physician (IFMCP)