Share: Researchers at the National Institutes of Health (NIH) have uncovered new details about how GLP-1 weight loss drugs such as semaglutide affect brain cells, revealing internal signaling processes that scientists have only begun to understand
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doi: 10.1126/science.aaz5891 Summary Keywords adverse reactions and cases, case report, depression, semaglutide, weight loss Citation Li J-R, Cao J, Wei J and Geng W (2023) Case Report: Semaglutide-associated depression: a report of two cases
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Study limitations include presence of statistical heterogeneity in the meta-analyses for change in HbA 1c and body weight, assessment of risk of bias solely for the primary outcome, and generalisation of findings mainly to individuals who are overweight or obese and already on metformin-based background therapy
Early time-restricted feeding improves 24-hour glucose levels and affects markers of the circadian clock, aging, and autophagy in humans
