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GLP-1GIPLani and GLP-1RGIPR co-agonism comparably induced G s recruitment (Extended Data Fig

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In addition, when comparing the costs across AOMs, Wegovy makes up most of 2022 plan spending at 58.4 percent, followed by Saxenda at 39.1 percent, as shown in the graph below

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Note that participants in the above trials used once-weekly injections of Wegovy in maintenance doses of up to 2.4 mg , which is currently the maximum recommended dose