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In both cases, there are important compliance and PBM contractual considerations that need to be explored and fully vetted as part of decision making

Among the SK channel members (SK1, SK2 and SK3), SK3 is expressed predominantly on neutrophils and the knockdown of SK3 in differentiated HL-60 (dHL-60) cells reduces the NETs formation induced by ionomycin-mediated NOX-independent NETosis

Notably, more than 30% of patients dropped out of treatment after the first month

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