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The liver relies on glutathione for detoxification reactions and for buffering oxidative byproducts created during normal metabolism

In a case report by Le at al, 22 a 36-year-old female patient developed DRESS four weeks following ingestion of a supplement consisting of DIM complex with diindolylmethane

Attenuated Gastric Ulcers, Seizures, Brain Lesions, Hepatomegaly, Fatty Liver, Breakdown of Liver Glycogen, Profound Hypoglycemia and Calcification in Rats

But there's also a lot of confusing and exaggerated information out there, especially around skin

Glutathione is a tripeptide, a small protein fragment, composed of three amino acids: glutamate, cysteine, and glycine

For example, the GSH intravenous administration in patients with Parkinsons disease determined significant improvements, which lasted for 24 months after the administration (26)