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In this hypothesis, the homozygous thermolabile MTHFR mutation would predispose to folate deficiency, which is likely to increase the cardiovascular disease risk by elevating homocysteine levels

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Comparing the expression pattern of NAPRT and NAMPT gene in human tumor cell lines versus normal tissues, the researchers found a great variability in mRNA and protein levels of NAPRT in tumor cells

doi: 10.1093/mp/ssp106 33 D'ArchivioMFilesiCDi BenedettoRGargiuloRGiovanniniCMasellaRet al

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"FDA Approves First New Molecular Entity Under National Priority Voucher Program"