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Patients should rotate injection sites systematically among the recommended areas: the abdomen (avoiding a 2-inch radius around the navel), the thigh, or the upper arm (with assistance from a caregiver or trained person)

This does not reflect typical prevalence of migraine development in this age group and it is likely that controls who developed migraine were more inclined to participate in the second study visit due to the onset of migraine

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The shape of your body may affect the injection process

Bellei B, Papaccio F, Filoni A, Caputo S, Lopez G, Migliano E

Patch testing before first use is recommended