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Nevertheless, ERRs regulate broad gene networks across heart, brain, kidney, and endocrine tissues

Omega-3 pathway: 18:3n-3 is metabolized to 18:4n-3, then to 20:4n-3, and 20:5n-3 (precursor to F3 isoprostanes, resolvins, hydroxy fatty acids, leukotrienes, and prostanoids)

Here's what the science shows: During perimenopause, hormonal shifts create an ideal moment to intervene and reduce future heart disease risk

Understanding these differences is essential for patients and healthcare providers when making informed treatment decisions

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