Gut & GI protection Derived from a gastric-juice protein and explored in preclinical work on protection of the stomach and intestinal lining
It functions as a highly specific inhibitor of an enzyme called NNMT (Nicotinamide N-methyltransferase)
Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia)
Studies have examined the relationship between NNMT inhibition and cellular NAD+ levels, which are critical for numerous enzymatic reactions including those involving sirtuins and PARPs
In many cases, individuals with B12 deficiency may receive injections once a week for several weeks, followed by less frequent maintenance injections, such as once a month
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