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That does not mean it is dangerous, but it does mean the clinician, not the patient, must carry the weight of the uncertainty

Well, this itself speaks volumes about the well-researched benefits of pre-workout supplements

JMIR Res Protoc

FDA accessdata.fda.gov (2025) 6

The decision to prescribe these medications should weigh the substantial metabolic benefits against individual gallbladder risk, recognizing that for most patients, the cardiovascular and glycemic advantages outweigh the relatively modest absolute risk increase

doi: 10.4049/jimmunol.166.12.7410