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In a double-blind, placebo-controlled crossover study involving men with erectile dysfunction (ED) of non-organic origin, MT2 induced clinically apparent erections in 8 out of 10 participants, with a mean duration of tip rigidity greater than 80% lasting 38 minutes, compared to only 3 minutes with a placebo

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Damaged mtDNA accumulation and fragmented mitochondria lead to increased production of ROS and activate apoptosis in the tubules (91)

In addition, our findings were existed to be similar to the outcomes of Pierik et al