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GLP-1 analogues Glucagon-like peptide-1 (GLP-1) receptor agonists are effective treatments for T2DM which lower glucose concentrations without weight gain (often with weight loss) and with low risk for hypoglycemia (Hinnen, 2017)

Following the PRISMA 2020 guidance, five databases were searched from inception to 30 September, 2025

Among them are the popular weight loss jabs Ozempic/Wegovy and Mounjaro/Zepbound, but similar compounds have been used for more than 18 years to treat type 2 diabetes

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Front Integr Neurosci