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Ipamorelin produces GH release without significant cortisol, prolactin, or ACTH elevation, making it the cleanest GHS-R1a agonist for isolated GH stimulation research
10.1038/tp.2016.77 154 UrakuboA.JarskogL
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As D23 could potentially form hydrogen bond with the activator, the loss of activity observed in the mutant supported such a model
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